Rybelsus is a brand name for the medication semaglutide, a prescription drug used to improve blood sugar control in adults with type 2 diabetes. It comes as a once-daily tablet taken orally.

Rybelsus belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. These medications mimic the effects of a natural hormone called glucagon-like peptide-1, which plays a crucial role in regulating blood sugar levels. Rybelsus primarily works in two ways:

• Increases insulin release: After eating, Rybelsus stimulates the release of insulin from the pancreas, the hormone responsible for ushering glucose (sugar) from the bloodstream into your cells for energy.
• Decreases glucagon secretion: Glucagon is another hormone produced by the pancreas that has the opposite effect of insulin, raising blood sugar levels. Rybelsus helps suppress the release of glucagon, preventing excessive sugar production and keeping your blood glucose levels in check.

• Improved glycemic control: Studies show Rybelsus can effectively lower A1C, a measure of average blood sugar control over the past three months. This can significantly reduce the risk of long-term complications associated with diabetes, such as nerve damage, vision problems, and kidney disease.
• Potential weight loss: While not the primary purpose, Rybelsus may also lead to weight loss in some individuals. This can be beneficial for people with type 2 diabetes, as excess weight can worsen blood sugar control.
• Reduced risk of cardiovascular events: Recent research suggests potential benefits of Rybelsus in reducing the risk of major adverse cardiovascular events, such as heart attack and stroke, in people with type 2 diabetes and high cardiovascular risk.
• Once-daily convenience: Rybelsus is a convenient one-daily tablet, promoting medication adherence compared to multiple daily doses of other medications.